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An active metabolite of L-leucine; reduces PIF-induced increases in 20S proteasome activity and NF-κB nuclear accumulation in C2C12 myotubes; inhibits protein degradation and stimulates protein synthesis in the gastrocnemius muscle of cachectic mice bearing MAC16 tumor at 0.25 and 2.5 g/kg; urinary levels are increased in patients with type II diabetes or ketoacidosis
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3-Methylvaleric Acid is a branched alkanoic acid utilized by Pseudomonas citronettotis as a sole carbon source. Its derivatives exhibit anti-hyperalgesic and anticonvulsant activities. This product is supplied as a 10 mM solution in 1 mL of DMSO.
Purity of 99.99%
Molecular weight of 116.16
Provided as a colorless to light yellow liquid
Recommended storage in solvent at -80°C for 6 months
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6-(N-Boc)caproic acid NHS is an N-hydroxysuccinimide (NHS) ester of Boc-protected caproic acid used as an amine-reactive linker and protein cross-linking reagent in bioconjugation and biochemical research. It provides an activated carboxylate for rapid coupling to primary amines and a tert-butyloxycarbonyl (Boc) protected spacer for selective deprotection after conjugation.
NHS-activated ester for efficient coupling to primary amines.
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Nonanoic acid is a naturally occurring saturated fatty acid composed of nine carbon atoms. It significantly reduces bacterial translocation, enhances antibacterial activity, and markedly increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2. It also upregulates endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition.
Naturally-occurring saturated fatty acid.
Reduces bacterial translocation.
Enhances antibacterial activity.
Increases secretion of porcine β-defensins 1 (pBD-1) and pBD-2.
Upregulates endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition.
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